First US Cancer Patients Are Undergoing CRISPR In New Gene-Editing Trial

A CRISPR clinical trial is currently underway at the University of Pennsylvania, where researchers are testing the efficacy of gene-editing technologies in treating cancer patients.

“To date, two patients with relapsed cancers – one with multiple myeloma and one with sarcoma – have been treated as part of this trial,” wrote Penn Medicine spokesperson in an email sent to IFLScience. “Findings from this research study will be shared at an appropriate time via a medical meeting presentation or peer-reviewed publication.”

CRISPR works by targeting certain genes responsible for certain functions or traits. When found, an enzyme called Cas9 binds to the DNA, “cuts” it, and shuts off that targeted gene. Beginning last fall, the team has begun the process of removing cells from the patients’ immune systems and modifying them in the lab, before introducing them back into the patients. Hopefully, those modified cells will target and destroy cancer cells, NPR first reported. No information is available about how well the procedure is working on the two patients, but researchers plan to eventually treat 18 patients with various forms of cancer by the close of the trial in 2033.


Recommended PRODUCTS
  • It Is A Step-by-step Guide For Women Interested In Better Understanding A Cancer Man.
  • Tips, tricks and real life experiences from a young breast cancer survivor.
  • This site teaches practically anyone how to change life with just a simple switch.
  • Put small animated peel image at the top corner right or left on webpage
  • Are you frustrated that your expensive karoke player does not let you play.
  • TRANSFORMING PHOTOS OF REAL PEOPLE INTO CARICATURES
  • The stunning secret of turning your wife on with the push of a button.
  • Learn about the solar systems largest planet jupiter predict great red spot transit times
  • Experience Rapid, Sustainable Fat Loss With A Gene Therapy Breakthrough.
  • Learn How To Attract the Man of Your Dreams And Receive A Marriage Proposal In Few Months
  • Get Highly Accurate Forex SignalsVery Reliable. Trial Us For Only 5
  • The Web's best resource for Ivy League applicants.
  • Discover How to Naturally and Permanently Take Back Your Life From Severe Psoriasis.
  • Helps You To Lose Weight In Just Four Weeks Without Strict Dieting And Exercise.
  • Discover how to boost your goal achieving skills in 30 days, guaranteed
  • Clickbank Ads
     
    An illustration shows the use of CRISPR to enhance CAR T cell-mediated killing of tumor cells through disruption of PD-1 protein. Targeted cells are extracted from the cancer patient, edited in the lab, and reinfused back into the body in hopes they will attack cancer cells. Meletios Verras/Shutterstock

    If successful, the trial is one of many that could revolutionize how diseases are prevented and treated.

    Earlier this year, concerns over the use of CRISPR were raised after Chinese researcher He Jiankui used the technology to modify the DNA of twin girls in an attempt to give them resistance to the human immunodeficiency virus (HIV) before the two were born, prompting a moratorium from the research community on such practices. This contentious research differs dramatically from the clinical trial involving cancer patients in that it was conducted on human embryos and created changes in heritable traits that could be passed down for generations to come. Rather, UPenn researchers are providing a medical treatment that only modifies the DNA of the participating individuals and, to their knowledge, would not result in potentially passing down altered genes to their children.

    As NPR notes, other human trials involving CRISPR are set to begin in the US, Canada, and Europe in order to test how well it can treat a variety of diseases, including two other US-based CRISPR studies designed to treat the genetic blood disorders sickle cell disease and beta thalassemia

     [H/T: NPR]

    Original Article : HERE ; This post was curated & posted using : RealSpecific

     


    RELATED PRODUCTS
  • This site teaches practically anyone how to change life with just a simple switch.
  • It Is A Step-by-step Guide For Women Interested In Better Understanding A Cancer Man.
  • Are you frustrated that your expensive karoke player does not let you play.
  • Tips, tricks and real life experiences from a young breast cancer survivor.
  • Put small animated peel image at the top corner right or left on webpage
  • College Admission Services For Ivy League Applicants.
  • Protect Your Family with Parental Controls Download Internet Filter Now
  • No Body Can Treat Your Sinus LikeUs. Safe Natural and 100 Effective
  • The Best RSS Autoblog Tool For Blogger Blogspot Blog.
  • Become A Certified Usui Reiki Healing Master With The Latest Reiki Certification Program.
  • Discover How To Add 20lbs To Your Bench Press, 15lbs To Deadlift, And 20lbs To Your Squat In 3 Months
  • Dont Let Social Anxiety Control Your Life Any Longer. Start Living.
  • Get Highly Accurate Forex SignalsVery Reliable. Trial Us For Only 5
  • A Truly Unique Extract Of The Greatest Methodologies For Keeping The Body And Mind Young And Agile.
  • Discover How Your Beliefs and Emotions Affect Your Ability To Achieve All Your Goals And Dreams.
  • Clickbank Ads
     

    Thank you for taking the time to read our article.

    If you enjoyed our content, we'd really appreciate some "love" with a share or two.

    And ... Don't forget to have fun!

    Recommended

    Stockocity 2 Reseller 3-Pay 20

    Reseller Privileges to 20 Accounts of Stockocity 2

    AutoSoci - CINEMATIC Edition (LITE)

    AutoSoci 2.5D Cinematography Edition Magnificently Attracts BUYERS Like Never Before With Your Unique Motion Effect Cinematic Images and Videos On Social Networks For More Profits On Autopilot.

    Leave a Reply